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Found 29 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit B'
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  12nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50393080(CHEMBL2152856)
Affinity DataKi:  30nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470392(CHEMBL4283208)
Affinity DataIC50:  3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470400(CHEMBL4289998)
Affinity DataIC50:  4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470403(CHEMBL4294467)
Affinity DataIC50:  4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470394(CHEMBL4281775)
Affinity DataIC50:  8nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470395(CHEMBL4279313)
Affinity DataIC50:  9nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470405(CHEMBL4289650)
Affinity DataIC50:  10nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470393(CHEMBL4291061)
Affinity DataIC50:  12nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470404(CHEMBL4279382)
Affinity DataIC50:  14nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470402(CHEMBL4278317)
Affinity DataIC50:  21nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470399(CHEMBL4286573)
Affinity DataIC50:  23nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470406(CHEMBL4295081)
Affinity DataIC50:  24nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470398(CHEMBL4286232)
Affinity DataIC50:  25nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470396(CHEMBL4293447)
Affinity DataIC50:  49nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50058509(CHEMBL3329317)
Affinity DataIC50:  86nMAssay Description:Inhibition of Staphylococcus aureus ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50393080(CHEMBL2152856)
Affinity DataIC50:  150nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 Par E subunit by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50173879(CHEMBL3810359)
Affinity DataIC50:  183nMAssay Description:Inhibition of Staphylococcus aureus DNA parE ATPase activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470401(CHEMBL4290062)
Affinity DataIC50:  200nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470397(CHEMBL4294536)
Affinity DataIC50:  400nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50006565(CHEMBL3235085)
Affinity DataIC50:  700nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50173878(CHEMBL3809316)
Affinity DataIC50:  746nMAssay Description:Inhibition of Staphylococcus aureus DNA parE ATPase activity incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50058511(CHEMBL3329318)
Affinity DataIC50:  780nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50058510(CHEMBL3329319)
Affinity DataIC50:  800nMAssay Description:Inhibition of Staphylococcus aureus ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50058509(CHEMBL3329317)
Affinity DataIC50:  940nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50470407(CHEMBL4286625)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Staphylococcus aures ParE using pBR322 DNA as substrate in presence of ATPMore data for this Ligand-Target Pair
TargetDNA topoisomerase 4 subunit B(Escherichia coli (strain K12))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50058510(CHEMBL3329319)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of Escherichia coli ParEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50550961(CHEMBL4764715)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Staphylococcus aures ParE using pBR322 DNA as substrate in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed