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Found 44 Enz. Inhib. hit(s) with Target = 'Dynamin-2'
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(CHEMBL1094197 | N,N'-(Propane-1,3-diyl)bis(6,7-dih...)
Affinity DataIC50:  290nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316539(CHEMBL1094850 | N,N'-(Ethane-1,2-diyl)bis(7,8-dihy...)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233983(CHEMBL4073116)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233972(CHEMBL4098509)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233969(CHEMBL4083788)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233975(CHEMBL4064353)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423885(CHEMBL2312431)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423888(CHEMBL2312414)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423886(CHEMBL2312428)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233996(CHEMBL4073407)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233981(CHEMBL4060114)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423887(CHEMBL2312415)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233972(CHEMBL4098509)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423883(CHEMBL2312430)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233969(CHEMBL4083788)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233976(CHEMBL4094056)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50423884(CHEMBL2312432)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233968(CHEMBL4082410)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233968(CHEMBL4082410)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233989(CHEMBL4090457)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055861(CHEMBL3329968)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233977(CHEMBL4086288)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316542(CHEMBL1098764 | N,N'-(Propane-1,3-diyl)bis(7,8-dih...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233961(CHEMBL4071476)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055860(CHEMBL3329967)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316541(CHEMBL1096801 | N,N'-(Propane-1,3-diyl)bis(7-hydro...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055859(CHEMBL3329966)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233981(CHEMBL4060114)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(CHEMBL1098763 | N,N'-(Propane-1,3-diyl)bis(8-hydro...)
Affinity DataIC50:  3.48E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233983(CHEMBL4073116)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318676(4-Chloro-2-{[2-(4-hydroxymethylphenyl)-1,3-dioxo-2...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Rattus norvegicus)
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50055862(CHEMBL3329969)
Affinity DataIC50:  4.37E+4nMAssay Description:Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50234000(CHEMBL4064810)
Affinity DataIC50:  4.74E+4nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316540(CHEMBL1098763 | N,N'-(Propane-1,3-diyl)bis(8-hydro...)
Affinity DataIC50:  4.82E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318675(4-Chloro-2-{[2-(3-nitrophenyl)-1,3-dioxo-2,3-dihyd...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50233975(CHEMBL4064353)
Affinity DataIC50:  6.59E+4nMAssay Description:Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318674(4-Chloro-2-{[2-(2-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316543(CHEMBL1094197 | N,N'-(Propane-1,3-diyl)bis(6,7-dih...)
Affinity DataIC50:  7.46E+4nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50318677(4-Chloro-2-{[2-(4-hydroxyphenyl)-1,3-dioxo-2,3-dih...)
Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-2(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50316539(CHEMBL1094850 | N,N'-(Ethane-1,2-diyl)bis(7,8-dihy...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed