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Found 2413 Enz. Inhib. hit(s) with Target = 'Histone-arginine methyltransferase CARM1'
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataKi:  23nM IC50:  83nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)
Affinity DataKi:  120nM IC50:  260nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataKi:  400nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataKi:  860nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396981(CHEMBL2171174)
Affinity DataKi: >2.00E+4nMAssay Description:Competitive inhibition of human CARM1 using oligo-nucleosome as substrate preincubated for 10 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Affinity DataKi: >3.75E+4nM IC50: >7.50E+4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396980(CHEMBL2171169)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50443018(CHEMBL3087503)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50443020(CHEMBL3087501)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50443019(CHEMBL3087502)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396977(CHEMBL2171172)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396978(CHEMBL2171171)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396981(CHEMBL2171174)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396980(CHEMBL2171169)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50396979(CHEMBL2171170)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of CARM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50258790((S)-2-amino-N-(3-(5-(5-(benzo[d]thiazol-7-yl)-1,3,...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301077(2-(4-(2-(2,6-dimethoxyphenyl)-7-methyl-1H-benzo[d]...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301079(2-(4-(2-(2-fluoro-6-methoxyphenyl)-7-methyl-1H-ben...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301078(2-(4-(2-(4-fluoro-2-methoxyphenyl)-7-methyl-1H-ben...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301076(2-(4-(2-(2-methoxyphenyl)-4-methyl-1H-benzo[d]imid...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301075(2-(4-(2-(2-methoxypyridin-3-yl)-3H-imidazo[4,5-b]p...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301069(2-(4-(2-(2-methoxypyridin-3-yl)-4-methyl-1H-benzo[...)
Affinity DataIC50:  0.840nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301073(2-(4-(2-(2-methoxypyridin-3-yl)-1H-benzo[d]imidazo...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301074(2-(4-(2-(2-methoxypyridin-3-yl)-1-methyl-1H-benzo[...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50598022(CHEMBL5173678)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT4 (2 to 608 residues) using histone H3 as substrate incubated for 20 mins in presence of [...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PRMT4 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation prox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PRMT4 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PRMT4 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301080(CHEMBL567298 | N-methyl-2-(4-(7-methyl-2-phenyl-1H...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50598021(CHEMBL5191769)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT4 (2 to 608 residues) using histone H3 as substrate incubated for 20 mins in presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50598020(CHEMBL5202088)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT4 (2 to 608 residues) using histone H3 as substrate incubated for 20 mins in presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194730(CHEMBL3906680)
Affinity DataIC50:  14nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194785(CHEMBL3956007)
Affinity DataIC50:  15nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194766(CHEMBL3938938)
Affinity DataIC50:  15nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194780(CHEMBL3911620)
Affinity DataIC50:  16nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194763(CHEMBL3957029)
Affinity DataIC50:  17nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50301070(2-(2-methoxypyridin-3-yl)-4-methyl-6-(piperidin-4-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CARM1 assessed as inhibition of histone3 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194759(CHEMBL3983725)
Affinity DataIC50:  17nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194775(CHEMBL3943629)
Affinity DataIC50:  18nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194776(CHEMBL3952337)
Affinity DataIC50:  18nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194768(CHEMBL3924657)
Affinity DataIC50:  19nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50525201(CHEMBL4463124)
Affinity DataIC50:  21nMAssay Description:Inhibition of PRMT4 (unknown origin) using histone H3 (21 to 44 residues) as substrate measured after 60 mins in presence of SAM by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194728(CHEMBL3984626)
Affinity DataIC50:  22nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194765(CHEMBL3925764)
Affinity DataIC50:  23nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50532879(CHEMBL3347611)
Affinity DataIC50:  27nMAssay Description:Inhibition of full-length GST-tagged CARM1 (unknown origin) using histone H3 substrate and [3H]SAM by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50158375(CHEMBL3781284)
Affinity DataIC50:  27nMAssay Description:Inhibition of GST-tagged CARM1 (unknown origin) using tritiated S-adenosylmethionine as substrate at 6 nM by methylation- based filter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194758(CHEMBL3970878)
Affinity DataIC50:  27nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50532879(CHEMBL3347611)
Affinity DataIC50:  27nMAssay Description:Inhibition of full-length GST-tagged CARM1 (unknown origin) using histone H3 substrate and [3H]SAM by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194764(CHEMBL3960002)
Affinity DataIC50:  28nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University Of Toronto

LigandPNGBDBM50194781(CHEMBL3929454)
Affinity DataIC50:  28nMAssay Description:Inhibition of human full length PRMT4 (1 to 608 residues) expressed in 293F cells assessed as inhibition of methylation activity preincubated with pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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