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Found 1005 Enz. Inhib. hit(s) with Target = 'M-phase inducer phosphatase 2'
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM41999(3-(3,4,5-trihydroxy-6-keto-xanthen-9-yl)propionic ...)
Affinity DataKi:  80nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50106497(6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataKi:  95nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26613((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...)
Affinity DataKi:  369nMAssay Description:Inhibition of N-terminal His-tagged Cdc25b catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50129580(3-[4,6-Dichloro-7-(3-methyl-but-2-enyl)-1H-indol-3...)
Affinity DataKi:  430nMAssay Description:Inhibitory constant of compound against Cell division cycle 25B was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50129574(2,5-Dihydroxy-3-[7-(3-methyl-but-2-enyl)-1H-indol-...)
Affinity DataKi:  640nMAssay Description:Inhibitory constant of compound against Cell division cycle 25B was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504064(CHEMBL4438316)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504065(CHEMBL4438470)
Affinity DataKi:  1.40E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50084504(CHEMBL3426991)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of His6-tagged human recombinant Cdc25B catalytic domain (350 to 566 residues) expressed in Escherichia coli BL21 (D3) after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50571956(CHEMBL4874608)
Affinity DataKi:  2.60E+3nMAssay Description:Competitive inhibition of recombinant human Cdc25B (351 to 380 residues) assessed as hydrolysis of substrate O-methylfluorescein phosphate by Linewea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504087(CHEMBL4587130)
Affinity DataKi:  2.70E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504063(CHEMBL4570006)
Affinity DataKi:  2.80E+3nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504067(CHEMBL4437577)
Affinity DataKi:  2.90E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50096680((E)-2-(2-Chloro-phenyl)-ethenesulfonic acid [4-(4-...)
Affinity DataKi:  4.60E+3nMAssay Description:In vitro inhibitory activity against human recombinant Cdc25B phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50388723(CHEMBL2057662)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of N-terminal His-tagged Cdc25b catalytic domain expressed in Escherichia coli BL21(DE3) using 3-O-Methylfluorescein phosphate as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504080(CHEMBL4525255)
Affinity DataKi:  4.90E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504081(CHEMBL4442999)
Affinity DataKi:  5.10E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DataKi:  5.30E+3nMAssay Description:Competitive reversible inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DataKi:  5.30E+3nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504068(CHEMBL4465468)
Affinity DataKi:  5.80E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504075(CHEMBL4521134)
Affinity DataKi:  6.10E+3nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504085(CHEMBL4585545)
Affinity DataKi:  6.40E+3nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504088(CHEMBL4434749)
Affinity DataKi:  6.50E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504070(CHEMBL4473428)
Affinity DataKi:  6.90E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504071(CHEMBL4470428)
Affinity DataKi:  7.10E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504086(CHEMBL4520431)
Affinity DataKi:  7.30E+3nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504066(CHEMBL4566865)
Affinity DataKi:  7.40E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504074(CHEMBL4447602)
Affinity DataKi:  8.50E+3nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504079(CHEMBL4464552)
Affinity DataKi:  9.90E+3nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504089(CHEMBL4449432)
Affinity DataKi:  1.19E+4nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504078(CHEMBL4551836)
Affinity DataKi:  1.25E+4nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50129575(2,5-Dihydroxy-3-(1H-indol-3-yl)-[1,4]benzoquinone ...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibitory constant of compound against Cdc25B phosphatase was determined using mFP as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504060(CHEMBL4592345)
Affinity DataKi:  1.34E+4nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504069(CHEMBL4552533)
Affinity DataKi:  1.69E+4nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504084(CHEMBL4443206)
Affinity DataKi:  2.20E+4nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504072(CHEMBL4561981)
Affinity DataKi:  3.00E+4nMAssay Description:Mixed inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504083(CHEBI:34876 | CHEMBL170408)
Affinity DataKi:  3.20E+4nMAssay Description:Mixed inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as substrate b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504082(CHEMBL4437090)
Affinity DataKi:  3.40E+4nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504073(CHEMBL4472907)
Affinity DataKi:  3.60E+4nMAssay Description:Mixed inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50096693((E)-2-Naphthalen-2-yl-ethenesulfonic acid (4,5-dip...)
Affinity DataKi:  3.60E+4nMAssay Description:Inhibitory activity against human recombinant Cdc25B phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504059(CHEMBL4465589)
Affinity DataKi:  3.60E+4nMAssay Description:Non-competitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504062(CHEMBL4439019)
Affinity DataKi:  4.50E+4nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504061(CHEMBL4452849)
Affinity DataKi:  5.40E+4nMAssay Description:Mixed inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50504076(CHEMBL4543585)
Affinity DataKi:  5.50E+4nMAssay Description:Uncompetitive inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM52026(2-(1-naphthoyl)benzoic acid | 2-(naphthalene-1-car...)
Affinity DataKi:  6.90E+4nMAssay Description:Mixed inhibition of N-terminal His6-tagged human CDC25B (377 to 550 residues) expressed in Escherichia coli BL21(DE3) cells using OMFP as substrate b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50388538(CHEMBL507159)
Affinity DataKi:  8.40E+4nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50328823(5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)dif...)
Affinity DataKi:  1.59E+5nMAssay Description:Competitive inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  70nMAssay Description:Inhibition of Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  80nMAssay Description:Inhibition of histidine-tagged full length human Cdc25B expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  100nMAssay Description:Inhibition of GST tagged Cdc25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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