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Found 2685 Enz. Inhib. hit(s) with Target = 'Melanocyte-stimulating hormone receptor'
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250661(US9447148, 9.30)
Affinity DataKi:  0.00500nM ΔG°:  -67.1kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50590042(CHEMBL5175981)
Affinity DataKi: >0.00549nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50131251((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataKi:  0.00600nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (hMC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250642(US9447148, 9.10)
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250653(US9447148, 9.22)
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250633(US9447148, 9.1)
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250652(US9447148, 9.21)
Affinity DataKi:  0.0100nM ΔG°:  -65.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250634(US9447148, 9.2 | US9447148, 9.31)
Affinity DataKi:  0.0120nM ΔG°:  -64.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250668(US9447148, 9.37 | US9447148, 9.50)
Affinity DataKi:  0.0140nM ΔG°:  -64.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250668(US9447148, 9.37 | US9447148, 9.50)
Affinity DataKi:  0.0140nM ΔG°:  -64.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250673(US9447148, 9.42 | US9447148, 9.55)
Affinity DataKi:  0.0150nM ΔG°:  -64.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250649(US9447148, 9.18)
Affinity DataKi:  0.0150nM ΔG°:  -64.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250673(US9447148, 9.42 | US9447148, 9.55)
Affinity DataKi:  0.0150nM ΔG°:  -64.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250658(US9447148, 9.27)
Affinity DataKi:  0.0150nM ΔG°:  -64.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250643(US9447148, 9.11)
Affinity DataKi:  0.0200nM ΔG°:  -63.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM85021(alpha-MSH, [Nle4, D-Phe7])
Affinity DataKi:  0.0231nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataKi:  0.0231nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250660(US9447148, 9.29)
Affinity DataKi:  0.0250nM ΔG°:  -62.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250651(US9447148, 9.20)
Affinity DataKi:  0.0250nM ΔG°:  -62.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250648(US9447148, 9.17)
Affinity DataKi:  0.0250nM ΔG°:  -62.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250659(US9447148, 9.28)
Affinity DataKi:  0.0300nM ΔG°:  -62.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250655(US9447148, 9.24)
Affinity DataKi:  0.0300nM ΔG°:  -62.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM82412(ALPHA-MSH | CAS_10466-28-1 | alpha MSH)
Affinity DataKi:  0.0334nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM82412(ALPHA-MSH | CAS_10466-28-1 | alpha MSH)
Affinity DataKi:  0.0334nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250635(US9447148, 9.3)
Affinity DataKi:  0.0400nM ΔG°:  -61.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250654(US9447148, 9.23)
Affinity DataKi:  0.0400nM ΔG°:  -61.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250671(US9447148, 9.40 | US9447148, 9.53)
Affinity DataKi:  0.0400nM ΔG°:  -61.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250671(US9447148, 9.40 | US9447148, 9.53)
Affinity DataKi:  0.0400nM ΔG°:  -61.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM82406(desacetyl-alpha-MSH)
Affinity DataKi:  0.0432nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM82406(desacetyl-alpha-MSH)
Affinity DataKi:  0.0432nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataKi:  0.0460nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC1 receptor expressed in BHK570 cells after 90 mins in presence of ovalbuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250672(US9447148, 9.41 | US9447148, 9.54)
Affinity DataKi:  0.0500nM ΔG°:  -61.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250672(US9447148, 9.41 | US9447148, 9.54)
Affinity DataKi:  0.0500nM ΔG°:  -61.2kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50590040(CHEMBL5185945)
Affinity DataKi:  0.0575nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250674(US9447148, 9.43)
Affinity DataKi:  0.0650nM ΔG°:  -60.5kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50581303(CHEMBL5087859)
Affinity DataKi:  0.0692nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250638(US9447148, 9.6)
Affinity DataKi:  0.0700nM ΔG°:  -60.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50165935(Ac-YRMEHdFRWGSPPKD-NH2 | CHEMBL414718)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250641(US9447148, 9.9)
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50165931(CHEMBL415165 | NDP-SYSMEHFRWGKPVG)
Affinity DataKi:  0.100nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM85022(alpha-MSH, [Nle4])
Affinity DataKi:  0.102nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50027084(Melatonan)
Affinity DataKi:  0.112nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM135768(US10179804, Example 153 | US10632171, Peptide No. ...)
Affinity DataKi:  0.120nM ΔG°:  -58.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50027084(Melatonan)
Affinity DataKi:  0.132nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50027084(Melatonan)
Affinity DataKi:  0.132nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50581298(CHEMBL5094168)
Affinity DataKi:  0.148nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM160170(US9040663, 16)
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM50358559(CHEMBL1923662)
Affinity DataKi:  0.170nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM250645(US9447148, 9.13)
Affinity DataKi:  0.195nM ΔG°:  -57.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies

US Patent
LigandPNGBDBM160159(US9040663, 5)
Affinity DataKi:  0.200nM ΔG°:  -57.6kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails US Patent
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