Found 1493 Enz. Inhib. hit(s) with Target = 'Kallikrein-5' 
Affinity DataKi: 0.340nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Inhibition of recombinant human KLK5 expressed in expressed in Pichia pastoris X-33 cells using Boc-VPR-MCA as susbtrate measured every 60 secs for 1...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Inhibition of recombinant KLK5 (unknown origin) expressed in Pichia pastoris X-33 cells using pNA peptide as susbtrate measured every 10 secs for 300...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 200nM ΔG°: -39.8kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 362nMAssay Description:Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry methodMore data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 500nM ΔG°: -37.4kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 500nM ΔG°: -37.4kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 500nM ΔG°: -37.4kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 600nM ΔG°: -36.9kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 600nM ΔG°: -36.9kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 600nM ΔG°: -36.9kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant human C-terminal 10His-tagged KLK5 (67 to 293 residues) expressed in mouse NS0 cells using fluorogenic Boc-VPR-AMC peptide ...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.00E+3nM ΔG°: -35.6kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.00E+3nM ΔG°: -35.6kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.00E+3nM ΔG°: -35.6kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Queensland University Of Technology
Curated by ChEMBL
Queensland University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.00E+3nM ΔG°: -35.6kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
