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Found 316 Enz. Inhib. hit(s) with Target = 'DNA polymerase beta'
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50293303(CHEMBL498103 | gallic acid 5,6-dihydroxy-3-carboxy...)
Affinity DataKi:  390nMAssay Description:Inhibition of DNA polymerase beta from human KB3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50253141([(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,...)
Affinity DataKi:  600nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50253100([(2R,3S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-...)
Affinity DataKi:  900nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50253142([(2R,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 mg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50109030(4-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition constant of the compound was determined at a concentration of 5 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50377969(CHEMBL1162297)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)
Affinity DataKi:  5.50E+3nMAssay Description:Competitive inhibition of recombinant rat DNA polymerase beta using poly(dA)/oligo(dT)18 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50109030(4-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition constant of the compound was determined at a concentration of 10 microM on rat DNA polymerase beta as a function of nucleotide substrate c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250426((+)-Myristinin A | CHEMBL465365)
Affinity DataKi:  1.10E+4nMAssay Description:Activity of rat recombinant DNA polymerase beta using variable levels of DNA template-primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)
Affinity DataKi:  1.16E+4nMAssay Description:Noncompetitive inhibition of recombinant rat DNA polymerase beta using dTTP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250427((+)-Myristinin D | CHEMBL448072)
Affinity DataKi:  1.20E+4nMAssay Description:Activity of rat recombinant DNA polymerase beta using variable levels of DNA template-primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50109029(4-{10,13-Dimethyl-3-[3-(6-{6-[5-(2-oxo-hexahydro-t...)
Affinity DataKi:  1.28E+4nMAssay Description:Inhibition constant of the compound was determined at a concentration of 5 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of activated calf thymus DNA and 0.1 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50109029(4-{10,13-Dimethyl-3-[3-(6-{6-[5-(2-oxo-hexahydro-t...)
Affinity DataKi:  2.01E+4nMAssay Description:Inhibition constant of the compound was determined at a concentration of 10 microM on rat DNA polymerase beta as a function of template primer doseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by uncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241570((24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | C...)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta after 20 mins by noncompetitive inhibition assay in presence of [3H]dTTP and 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50408425(CHEMBL2092835)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50408425(CHEMBL2092835)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250427((+)-Myristinin D | CHEMBL448072)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in absence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50241922(CHEMBL486991 | ddCTP SODIUM | sodium ((2S,5R)-5-(4...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50164648(2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human DNA polymerase-betaMore data for this Ligand-Target Pair
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335554(({[({[2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)e...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human DNA polymerase beta by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50184757((3aR,4R,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50259787(3-trans-p-coumaroyl maslinic acid | CHEMBL453751)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50408426(CHEMBL2092833)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292441(1beta-hydroxyaleuritolic acid 3-p-hydroxybenzoate ...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50184758((3aS,4S,7R,7aR)-1,6-didodecyl-2,7-bis(methoxycarbo...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50184756((3aR,4S,7S,7aS)-7-ethyl 2,4-dimethyl 3,5-dihexadec...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50259782(3beta-hydroxyrus-18,20(30)-dien-28-oic acid | CHEM...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250426((+)-Myristinin A | CHEMBL465365)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in absence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250305(3alpha-O-trans-p-coumaroyl-7-labden-15-oic acid | ...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50184755((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(methoxycar...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50259781(3beta-hydroxyrus-12,19(29)-dien-28-oic acid | CHEM...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50079577((4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50259787(3-trans-p-coumaroyl maslinic acid | CHEMBL453751)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of 0.1 mg/mL BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250427((+)-Myristinin D | CHEMBL448072)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50184752((3aS,4S,7R,7aR)-1,6-dihexadecyl-2,7-bis(isopropoxy...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50250305(3alpha-O-trans-p-coumaroyl-7-labden-15-oic acid | ...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50259781(3beta-hydroxyrus-12,19(29)-dien-28-oic acid | CHEM...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50259782(3beta-hydroxyrus-18,20(30)-dien-28-oic acid | CHEM...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of rat DNA polymerase beta in presence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50203241(1, 3-dihydroxy-5-[14'-(3' ',5' '-dihydroxyphenyl)t...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta in absence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241611(1, 3-dihydroxy-5-[14'-(3' ',5' '-dihydroxyphenyl)-...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027113(2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18...)
Affinity DataIC50:  6.60E+3nMAssay Description:Ability to inhibit mouse beta DNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50027121(2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18...)
Affinity DataIC50:  7.40E+3nMAssay Description:Ability to inhibit mouse beta DNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50250356((+)-protolichesterinic acid | CHEMBL490329 | proto...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50241610(1,3-dihydroxy-5-[14'-(3' ',5' '-dihydroxyphenyl)-c...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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