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Found 669 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent glycine transporter 2'
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50122872(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023929(CHEMBL3325502)
Affinity DataIC50:  15nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human GlyT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human GlyT2 stably expressed in CHO cells assessed as reduction in [3H]glycine uptake incubated for 10 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102692(4-Benzyloxy-N-(1-dimethylamino-cyclopentylmethyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human GlyT-2 expressed in CHO cells assessed as reduction in [3H]-glycine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138590(2-(7-Hydroxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537022(CHEMBL4587165)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50256745((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human GlyT2 expressed in porcine aorta epithelial cells assessed as reduction in [3H]-Glycine uptake at pH 7.5 by scintillation spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537040(CHEMBL4515597)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138578(2-(7-Hydroxy-1-methyl-3,4-dihydro-1H-isoquinolin-2...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537034(CHEMBL4572247)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50203568((1-(4-(6-((5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138594(2-(5-Hydroxy-1,3-dihydro-isoindol-2-ylmethyl)-N-(4...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138558(2-[(6-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-ylam...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537044(CHEMBL4562565)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537033(CHEMBL4535356)
Affinity DataIC50:  48nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023797(CHEMBL3325511)
Affinity DataIC50:  52nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537043(CHEMBL4227139)
Affinity DataIC50:  55nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138584(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-((E...)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138559(2-(7-Hydroxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-y...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023926(CHEMBL3325505)
Affinity DataIC50:  62nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537049(CHEMBL4527071)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023866(CHEMBL3325509)
Affinity DataIC50:  66nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138556(2-(7-Hydroxy-3-methyl-3,4-dihydro-1H-isoquinolin-2...)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537023(CHEMBL4542099)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023928(CHEMBL3325503)
Affinity DataIC50:  71nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138565(CHEMBL348200 | N-[4-(4-Chloro-phenyl)-butyl]-2-{[2...)
Affinity DataIC50:  77nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102687(4-Butoxy-N-(1-dimethylamino-cyclopentylmethyl)-3,5...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023930(CHEMBL3325501)
Affinity DataIC50:  80nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138555(2-[(6-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-ylam...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50102688(4-Benzyloxy-N-(1-dimethylamino-cyclohexylmethyl)-3...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138561(2-{[2-(4-Hydroxy-phenyl)-ethylamino]-methyl}-N-(4-...)
Affinity DataIC50:  86nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138569(2-(7-Hydroxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537054(CHEMBL4549008)
Affinity DataIC50:  91nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138572(CHEMBL153410 | N-[4-(3-Chloro-phenyl)-butyl]-2-{[2...)
Affinity DataIC50:  99nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023874(CHEMBL3325508)
Affinity DataIC50:  99nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50256745((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)
Affinity DataIC50:  100nMAssay Description:Inhibition of full length human GlyT2 expressed in FreeStyle 293-F suspension cells incubated for 30 mins before [3H]glycine addition and measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50256745((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human GlyT-2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake preincubated for 30 mins followed by 3H]-glycine ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50:  105nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50:  105nMAssay Description:Inhibition of human GlyT-2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023924(CHEMBL3325507)
Affinity DataIC50:  105nMAssay Description:Reversible inhibition of recombinant human GlyT2 expressed in HEK293 cells assessed as reduction in [3H]-glycine uptake after 2 hrs by top count assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023925(CHEMBL3325506)
Affinity DataIC50:  107nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rattus norvegicus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023993(CHEMBL3325495)
Affinity DataIC50:  112nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50023932(CHEMBL3325499)
Affinity DataIC50:  115nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138587(CHEMBL348211 | N-[4-(3,4-Dichloro-phenyl)-butyl]-2...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50138592(2-(6-Hydroxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50537031(CHEMBL4540633)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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