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Found 418 Enz. Inhib. hit(s) with Target = 'Hepatic triacylglycerol lipase'
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151423(US8987314, B234)
Affinity DataIC50:  0.5nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151421(US8987314, B232)
Affinity DataIC50:  0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50525871(CHEMBL4460999)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of hepatic lipase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151465(US8987314, B276)
Affinity DataIC50:  0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151397(US8987314, B208)
Affinity DataIC50:  0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151266(US8987314, B62)
Affinity DataIC50:  1nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151494(US8987314, B305)
Affinity DataIC50:  1nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151441(US8987314, B252)
Affinity DataIC50:  1.40nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151496(US8987314, B307)
Affinity DataIC50:  1.5nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151268(US8987314, B64)
Affinity DataIC50:  1.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151399(US8987314, B210)
Affinity DataIC50:  1.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50506499(CHEMBL4463265)
Affinity DataIC50:  2nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151554(US8987314, B365)
Affinity DataIC50:  2.10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151292(US8987314, B88)
Affinity DataIC50:  2.20nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151432(US8987314, B243)
Affinity DataIC50:  2.40nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151267(US8987314, B63)
Affinity DataIC50:  2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151291(US8987314, B87)
Affinity DataIC50:  2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151473(US8987314, B284)
Affinity DataIC50:  2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151468(US8987314, B279)
Affinity DataIC50:  2.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151396(US8987314, B207)
Affinity DataIC50:  2.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151409(US8987314, B220)
Affinity DataIC50:  2.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151469(US8987314, B280)
Affinity DataIC50:  2.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187287(US9169240, 27)
Affinity DataIC50:  3nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151402(US8987314, B213)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151462(US8987314, B273)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151422(US8987314, B233)
Affinity DataIC50:  3.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151406(US8987314, B217)
Affinity DataIC50:  3.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151404(US8987314, B215)
Affinity DataIC50:  3.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50506506(CHEMBL4465833)
Affinity DataIC50:  4nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50506505(CHEMBL4460376)
Affinity DataIC50:  4nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187290(US9169240, 30)
Affinity DataIC50:  5nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151463(US8987314, B274)
Affinity DataIC50:  5.10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151407(US8987314, B218)
Affinity DataIC50:  5.20nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50525869(CHEMBL4587475)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of hepatic lipase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151567(US8987314, B378)
Affinity DataIC50:  6.70nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50522804(CHEMBL4437751)
Affinity DataIC50:  7nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151297(US8987314, B93)
Affinity DataIC50:  7.10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151428(US8987314, B239)
Affinity DataIC50:  7.30nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151412(US8987314, B223)
Affinity DataIC50:  7.70nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50506500(CHEMBL4471611)
Affinity DataIC50:  9nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151442(US8987314, B253)
Affinity DataIC50:  9.40nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50521232(CHEMBL4567596)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151331(US8987314, B129)
Affinity DataIC50: <10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50521233(CHEMBL4458141)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50521230(CHEMBL4546575)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50521225(CHEMBL4440746)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50521236(CHEMBL4589925)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187289(US9169240, 29)
Affinity DataIC50:  10nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50506497(CHEMBL4446812)
Affinity DataIC50:  10nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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