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Found 13 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily KQT member 3'
TargetPotassium voltage-gated channel subfamily KQT member 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KCNQ3 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465777(CHEMBL4288707)
Affinity DataEC50:  200nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465774(CHEMBL4287894)
Affinity DataEC50:  360nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465779(CHEMBL4278049)
Affinity DataEC50:  80nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465778(CHEMBL4287478)
Affinity DataEC50:  400nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3(Rattus norvegicus)
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50601513(CHEMBL5180351)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat KCNQ2/3 channel expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50420049(CHEMBL402146)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465775(CHEMBL1703636)
Affinity DataEC50:  500nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | EZOGABINE | N-(2-amino-4-(4-fluorobe...)
Affinity DataEC50:  3.90E+3nMAssay Description:Activation of human Kv7.3 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily KQT member 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50526876(CHEMBL4457044)
Affinity DataEC50:  920nMAssay Description:Activation of human Kv7.3 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50526877(CHEMBL4545892)
Affinity DataEC50:  1.05E+4nMAssay Description:Activation of human Kv7.3 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426567(BMS-204352 | FLINDOKALNER | MaxiPost)
Affinity DataEC50:  2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 3/5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50465773(CHEMBL4277250)
Affinity DataEC50:  250nMAssay Description:Activation of human Kv7.3/7.5 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed