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Found 36 Enz. Inhib. hit(s) with Target = 'Methylcytosine dioxygenase TET2'
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570891(CHEMBL4872206)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of TET2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590161(CHEMBL5193408)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590162(CHEMBL5205660)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570898(CHEMBL4860506)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570897(CHEMBL4872110)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation by measu...More data for this Ligand-Target Pair
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590161(CHEMBL5193408)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590171(CHEMBL5177215)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM47715(DEFEROXAMINE | DEFEROXAMINE MESYLATE | MLS00002871...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation by measu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570894(CHEMBL4855677)
Affinity DataIC50:  5.48E+4nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of TET2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50508775(CHEMBL4457636)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of recombinant human C-terminal His/N-terminal FLAG-tagged TET2 (1129 to 2002 residues) expressed in baculovirus infected sf9 cells assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590168(CHEMBL5199439)
Affinity DataIC50:  8.66E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570896(CHEMBL4847806)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570895(CHEMBL4859276)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590165(CHEMBL5194069)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590177(CHEMBL5170671)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590176(CHEMBL5186458)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590175(CHEMBL5169988)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590174(CHEMBL5203367)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590163(CHEMBL5198202)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590164(CHEMBL5207325)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590166(CHEMBL5196825)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590167(CHEMBL5205573)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590169(CHEMBL5173988)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590170(CHEMBL5198851)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590172(CHEMBL5183202)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590173(CHEMBL5195222)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570892(CHEMBL4870693)
Affinity DataIC50:  2.62E+5nMAssay Description:Inhibition of recombinant human GST-tagged TET2 (1099 to 1936 residues) expressed in Escherichia coli BL21 (DE3)pLysS assessed as reduction in 5hmc l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570894(CHEMBL4855677)
Affinity DataKd:  610nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570892(CHEMBL4870693)
Affinity DataKd:  3.42E+3nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570893(CHEMBL4851104)
Affinity DataKd:  300nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethylcytosine dioxygenase TET2(Homo sapiens)
Taussig Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570895(CHEMBL4859276)
Affinity DataKd:  2.05E+3nMAssay Description:Binding affinity to human recombinant TET2 (1099 to 1936) catalytic domain assessed as dissociation constant by micro-scale thermophoresis analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed