Compile Data Set for Download or QSAR
maximum 50k data
Found 238 Enz. Inhib. hit(s) with Target = 'Sonic hedgehog protein'
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443885(CHEMBL3091556)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443912(CHEMBL3091466)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443889(CHEMBL3091552)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443903(CHEMBL3091565)
Affinity DataIC50:  1nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443896(CHEMBL3091572)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443902(CHEMBL3091566)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443892(CHEMBL3091549)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443920(CHEMBL3091729)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443894(CHEMBL3091574)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443913(CHEMBL3091736)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443921(CHEMBL3091577)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443891(CHEMBL3091550)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443893(CHEMBL3091548)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443887(CHEMBL3091554)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443890(CHEMBL3091551)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443915(CHEMBL3091734)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443897(CHEMBL3091571)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443900(CHEMBL3091568)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443905(CHEMBL3091563)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249185(4-(4-cyclopropylquinazolin-2-ylamino)-N-(2,6-dimet...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443917(CHEMBL3091732)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421186(CHEMBL2086800)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249186(CHEMBL472802 | N-(2,6-dimethylphenyl)-4-(4-phenylp...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401324(CHEMBL2205229)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401323(CHEMBL2205230)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401328(CHEMBL2087239)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401328(CHEMBL2087239)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401325(CHEMBL2205228)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421184(CHEMBL2086798)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443888(CHEMBL3091553)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394562(ERISMODEGIB | LDE225 | N-(6-((2S,6R)-2,6-dimethylm...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401329(CHEMBL2205225)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249184(CHEMBL515093 | N-(1-methyl-1,2,3,4-tetrahydroquino...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421190(CHEMBL2086805)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401326(CHEMBL2205227)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421187(CHEMBL2086801)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50302111(CHEMBL572255 | N-(4-chloro-3-(1-methyl-1H-benzo[d]...)
Affinity DataIC50:  9nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421193(CHEMBL2086802)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443910(CHEMBL3091558)
Affinity DataIC50:  11nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50302139(CHEMBL570273 | N-(3-(1H-benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  12nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  13nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401330(CHEMBL2205224)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human SHH pathway in mouse S12 cells assessed as GLI-mediated transcriptional activity after 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443909(CHEMBL3091559)
Affinity DataIC50:  16nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249488(4-benzyl-N-((3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50443916(CHEMBL3091733)
Affinity DataIC50:  20nMAssay Description:Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421189(CHEMBL2086804)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
Jiangsu Simcere Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421188(CHEMBL2086803)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 238 total ) | Next | Last >>
Jump to: