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Found 37 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 1/2'
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50463542(CHEMBL4243009)
Affinity DataIC50:  4.92E+4nMAssay Description:Antagonist activity at FLAG-tagged human TLR2/TLR1 expressed in HEK293 cells co-expressing pGL3-Elam.luc assessed as inhibition of Pam3CSK4-stimulate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577381(US11472815, Compound 2)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577382(US11472815, Compound 3)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577383(US11472815, Compound 4)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577384(US11472815, Compound 5)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577385(US11472815, Compound 9)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577386(US11472815, Compound 11)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577387(US11472815, Compound 15)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577388(US11472815, Compound 18)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577389(US11472815, Compound 21)
Affinity DataEC50:  24.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50552134(CHEMBL4759149 | US11472815, Compound 22)
Affinity DataEC50:  4.88nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577391(US11472815, Compound 23)
Affinity DataEC50:  5.14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577392(US11472815, Compound 24)
Affinity DataEC50:  433nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577393(US11472815, Compound 25)
Affinity DataEC50:  45.6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577394(US11472815, Compound 26)
Affinity DataEC50:  192nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577395(US11472815, Compound 27)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577396(US11472815, Compound 28)
Affinity DataEC50:  92.3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577397(US11472815, Compound 29)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577398(US11472815, Compound 30)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577399(US11472815, Compound 31)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577400(US11472815, Compound 32)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577401(US11472815, Compound 33)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577402(US11472815, Compound 34)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577403(US11472815, Compound 35)
Affinity DataEC50:  18.8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577404(US11472815, Compound 36)
Affinity DataEC50:  56.3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577405(US11472815, Compound 37)
Affinity DataEC50:  113nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577406(US11472815, Compound 38)
Affinity DataEC50:  16.9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577407(US11472815, Compound 39)
Affinity DataEC50:  12nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577408(US11472815, Compound 40)
Affinity DataEC50:  49.1nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577409(US11472815, Compound 41)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577410(US11472815, Compound 42)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577411(US11472815, Compound 43)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577412(US11472815, Compound 44)
Affinity DataEC50:  764nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577413(US11472815, Compound 45)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577414(US11472815, Compound 46 | US11472815, Compound 47)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577414(US11472815, Compound 46 | US11472815, Compound 47)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 1/2(Homo sapiens (Human))
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM577380(US11472815, Compound 1)
Affinity DataEC50: >1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent