TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysisMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 1.31E+3nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of RANK binding to human RANKL measured after 1 h by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 2.84E+5nMAssay Description:Binding affinity to human RANKL by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 2.70E+3nMAssay Description:Binding affinity to human RANKL by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Mus musculus)
Sookmyung Women'S University
Curated by ChEMBL
Sookmyung Women'S University
Curated by ChEMBL
Affinity DataKd: 1.73E+4nMAssay Description:Binding affinity to mouse N-terminal His6-Trx-tagged RANKL ectodomain (157 to 316 residues) expressed in Escherichia coli BL21 (DE3) by isothermal ti...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to human RANKL by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 3.09E+4nMAssay Description:Binding affinity to recombinant human sRANKL expressed in Escherichia coli by SPR assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 4.54E+3nMAssay Description:Binding affinity to recombinant human sRANKL expressed in Escherichia coli by SPR assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 2.75E+3nMAssay Description:Binding affinity to recombinant human sRANKL expressed in Escherichia coli by SPR assayMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 5.03E+3nMAssay Description:Binding affinity to human RANKL assessed as dissociation constant by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.38E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 8.71E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 5.24E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 4.90E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 6.62E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: >1.10E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 2.18E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: >2.50E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.76E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.91E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.10E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 2.23E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 3.55E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: >1.50E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 1.25E+4nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 2.82E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 8.49E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair