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BDBM26190 1,4-Dihydroxybenzene, XIII::1,4-dihydroxybenzene::CHEMBL537::Hydroquinone (9)::Hydroquinone, HQ::benzene-1,4-diol::phenol derivative, 4
SMILES: Oc1ccc(O)cc1
InChI Key: InChIKey=QIGBRXMKCJKVMJ-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Erzurum Technical University Curated by ChEMBL | Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Bur... | Bioorg Med Chem 24: 2318-29 (2016) Article DOI: 10.1016/j.bmc.2016.04.002 BindingDB Entry DOI: 10.7270/Q2930W3J | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 90 | -9.61 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (docked) | ||||||||||||
| Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay | Bioorg Med Chem Lett 18: 3593-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.077 BindingDB Entry DOI: 10.7270/Q2XP75TC | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University | Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. | J Enzyme Inhib Med Chem 27: 880-5 (2012) Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Carbonic anhydrase (Dicentrarchus labrax) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/TrEMBL GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gumushane University Curated by ChEMBL | Assay Description Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assay | Bioorg Med Chem Lett 21: 4259-62 (2011) Article DOI: 10.1016/j.bmcl.2011.05.071 BindingDB Entry DOI: 10.7270/Q2PC32Q0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.20E+3 | -6.93 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 15 (Mus musculus) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assay | Bioorg Med Chem Lett 18: 3593-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.077 BindingDB Entry DOI: 10.7270/Q2XP75TC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay | Bioorg Med Chem Lett 18: 3593-6 (2008) Article DOI: 10.1016/j.bmcl.2008.04.077 BindingDB Entry DOI: 10.7270/Q2XP75TC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.07E+4 | -6.78 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University | Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. | J Enzyme Inhib Med Chem 27: 880-5 (2012) Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University | Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. | J Enzyme Inhib Med Chem 27: 880-5 (2012) Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 5B, mitochondrial (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 13 (Mus musculus (mouse)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 6 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 6 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.24E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Agri Ibrahim Cecen University | Assay Description Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate. | J Enzyme Inhib Med Chem 27: 880-5 (2012) Article DOI: 10.3109/14756366.2011.637202 BindingDB Entry DOI: 10.7270/Q2VH5MRR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.83E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... | Bioorg Med Chem 16: 7424-8 (2008) Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prolyl 4-hydroxylase subunit alpha-1 (Gallus gallus (Chicken)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.40E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu | Assay Description Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase. | J Biol Chem 261: 7819-23 (1986) BindingDB Entry DOI: 10.7270/Q2SJ1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungnam National University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase activity after 10 mins | J Nat Prod 71: 995-9 (2008) Article DOI: 10.1021/np800002z BindingDB Entry DOI: 10.7270/Q2BK1C49 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AmorePacific Corporation Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase activity after 20 mins | Bioorg Med Chem Lett 19: 1532-3 (2009) Article DOI: 10.1016/j.bmcl.2008.12.106 BindingDB Entry DOI: 10.7270/Q2KK9BNT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosinase (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Grenoble Alpes Curated by ChEMBL | Assay Description Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assay | J Med Chem 63: 13428-13443 (2020) Article DOI: 10.1021/acs.jmedchem.0c00994 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungnam National University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase after 10 mins by spectrophotometry | J Nat Prod 72: 1205-8 (2009) Article DOI: 10.1021/np900031q BindingDB Entry DOI: 10.7270/Q2QF8T0K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pusan National University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase | Bioorg Med Chem Lett 20: 4882-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.087 BindingDB Entry DOI: 10.7270/Q26M370Q | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Mayoly Spindler S.A. Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase | Bioorg Med Chem Lett 18: 3607-10 (2008) Article DOI: 10.1016/j.bmcl.2008.04.079 BindingDB Entry DOI: 10.7270/Q22F7PB4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.76E+4 | n/a | n/a | n/a | n/a | 6.8 | 25 |
National Tsing Hua University | Assay Description The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period. | J Enzyme Inhib Med Chem 23: 526-34 (2008) Article DOI: 10.1080/14756360701654894 BindingDB Entry DOI: 10.7270/Q29885MB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosinase (Mus musculus (Mouse)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.88E+5 | n/a | n/a | n/a | n/a | 6.8 | 25 |
National Tsing Hua University | Assay Description The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period. | J Enzyme Inhib Med Chem 23: 526-34 (2008) Article DOI: 10.1080/14756360701654894 BindingDB Entry DOI: 10.7270/Q29885MB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanyang University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 20 mins by spectrophotometry | Bioorg Med Chem Lett 22: 4159-62 (2012) Article DOI: 10.1016/j.bmcl.2012.04.046 BindingDB Entry DOI: 10.7270/Q23J3GV6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.09E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Catholic University of C£rdoba Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysis | Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Catholic University of C£rdoba Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase using as L-tyrosine substrate after 10 mins by spectrophotometric analysis | Bioorg Med Chem 19: 3474-82 (2011) Article DOI: 10.1016/j.bmc.2011.04.025 BindingDB Entry DOI: 10.7270/Q22Z18DZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosinase (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human tyrosinase | J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tyrosinase (Homo sapiens (Human)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human tyrosinase | J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cheng Kung University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase | J Nat Prod 65: 1452-6 (2002) Article DOI: 10.1021/np020188v BindingDB Entry DOI: 10.7270/Q2PC324C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
National Cheng Kung University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase by spectrophotometry | J Nat Prod 67: 437-40 (2004) Article DOI: 10.1021/np0302854 BindingDB Entry DOI: 10.7270/Q2TX3F4P | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom)) | BDBM26190 (1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...) | UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pusan National University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase | Bioorg Med Chem Lett 17: 461-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.025 BindingDB Entry DOI: 10.7270/Q20P0ZNM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kcal/mole | -TΔS° kcal/mole | ΔH° kcal/mole | log K | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|
BDBM36284 | BDBM26190 | PC cid PC sid | CHEBI KEGG MMDB PC cid PC sid PDB | -4.94 | n/a | n/a | 3.62 | 7 | 25 | |
University of Cambridge | J Phys Chem B 114: 8606-15 (2010) | |||||||||
