BDBM50006243 ((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium::(4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium; iodide::CHEMBL12587::CHEMBL292911
SMILES: C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O
InChI Key: InChIKey=UQOFGTXDASPNLL-XHNCKOQMSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity | Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M4 in CHO cell membranes | J Med Chem 43: 2514-22 (2000) Article DOI: 10.1021/jm9904001 BindingDB Entry DOI: 10.7270/Q29W0DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H]- quinuclidinyl benzilate binding to human Muscarinic acetylcholine receptor M2 expressed in CHO cell membrane | J Med Chem 43: 2514-22 (2000) Article DOI: 10.1021/jm9904001 BindingDB Entry DOI: 10.7270/Q29W0DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of [3H]oxotremorine M to Muscarinic acetylcholine receptor M1 in rat cerebral cortical membranes | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Affinity versus [3H]oxotremorine M (agonist) binding to Muscarinic acetylcholine receptor M1 in Rat Cerebral Cortical Membranes, (Kd=0.75 nM) | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M1 expressed in CHO cell membranes | J Med Chem 43: 2514-22 (2000) Article DOI: 10.1021/jm9904001 BindingDB Entry DOI: 10.7270/Q29W0DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H]- oxotremorine-M binding to human Muscarinic acetylcholine receptor M2 expressed in CHO cell membranes | J Med Chem 43: 2514-22 (2000) Article DOI: 10.1021/jm9904001 BindingDB Entry DOI: 10.7270/Q29W0DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of [3H]quinuclidinyl benzilate to muscarinic receptors in membranes of CHO cells transfected with Muscarinic acetylcholine rece... | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL | Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M3 of rat sabmandibular glands | J Med Chem 35: 1915-20 (1992) Article DOI: 10.1021/jm00088a029 BindingDB Entry DOI: 10.7270/Q2ZS2VF5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 and M5 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Binding affinity to human cloned muscarinic M2 receptor expressed in CHO cells | Bioorg Med Chem 16: 3049-58 (2008) Article DOI: 10.1016/j.bmc.2007.12.036 BindingDB Entry DOI: 10.7270/Q2MS3WJ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M4 in rat cerebral cortical membranes | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of [3H]- quinuclidinyl benzilate binding to Muscarinic acetylcholine receptor M4 expressed in CHO cell membranes | J Med Chem 43: 2514-22 (2000) Article DOI: 10.1021/jm9904001 BindingDB Entry DOI: 10.7270/Q29W0DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article | 5.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity | Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL | Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M1 of rat cerebral cortex. | J Med Chem 35: 1915-20 (1992) Article DOI: 10.1021/jm00088a029 BindingDB Entry DOI: 10.7270/Q2ZS2VF5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Binding affinity to human cloned muscarinic M1 receptor expressed in CHO cells | Bioorg Med Chem 16: 3049-58 (2008) Article DOI: 10.1016/j.bmc.2007.12.036 BindingDB Entry DOI: 10.7270/Q2MS3WJ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL | Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M2 of rat heart. | J Med Chem 35: 1915-20 (1992) Article DOI: 10.1021/jm00088a029 BindingDB Entry DOI: 10.7270/Q2ZS2VF5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of [3H]quinuclidinyl benzilate to muscarinic receptors in membranes of CHO cells transfected with Muscarinic acetylcholine rece... | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected... | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 449 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the absence of GTP | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of binding of 0.1 nM [3H]quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat cerebral cortical membranes of transfected... | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari... | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 219 | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibitory activity against stimulation of [3H]inositol monophosphate accumulation in [3H]inositol-labelled CHO transfected cells mediated by Muscari... | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Sandoz Pharma Ltd Curated by ChEMBL | Assay Description Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model) | J Med Chem 35: 15-27 (1992) Article DOI: 10.1021/jm00079a002 BindingDB Entry DOI: 10.7270/Q29022RV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M4 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibitory activity against [3H]-cyclic AMP accumulation in CHO transfected cells mediated by Muscarinic acetylcholine receptor M4 | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 and M4 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.45E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 and M4 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibitory activity against [3H]quinuclidinyl Benzilate binding to Muscarinic acetylcholine receptor M2 in the presence of GTP | J Med Chem 41: 2047-55 (1998) Article DOI: 10.1021/jm9705115 BindingDB Entry DOI: 10.7270/Q2B27VZZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sandoz Pharma Ltd Curated by ChEMBL | Assay Description Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue. | J Med Chem 35: 15-27 (1992) Article DOI: 10.1021/jm00079a002 BindingDB Entry DOI: 10.7270/Q29022RV | |||||||||||
More data for this Ligand-Target Pair |