BDBM50032963 (S)-4-Amino-3-(4-chloro-phenyl)-butyric acid::BACLOFEN::CHEMBL302213

SMILES: NC[C@@H](CC(O)=O)c1ccc(Cl)cc1

InChI Key: InChIKey=KPYSYYIEGFHWSV-MRVPVSSYSA-N

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-B receptor 1/2 (Rattus norvegicus (Rat))	BDBM50032963 ((S)-4-Amino-3-(4-chloro-phenyl)-butyric acid | BAC...) Show SMILES NC[C@@H](CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>140	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor				J Med Chem 42: 2053-9 (1999) Article DOI: 10.1021/jm990076+ BindingDB Entry DOI: 10.7270/Q2WW7GV9
					More data for this Ligand-Target Pair
GABA-B receptor 1/2 (Homo sapiens (Human))	BDBM50032963 ((S)-4-Amino-3-(4-chloro-phenyl)-butyric acid | BAC...) Show SMILES NC[C@@H](CC(O)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy AG Curated by ChEMBL					Assay Description Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellum				J Med Chem 38: 3297-312 (1995) Article DOI: 10.1021/jm00017a015 BindingDB Entry DOI: 10.7270/Q2N58KDP
					More data for this Ligand-Target Pair