BindingDB logo
myBDB logout

BDBM50311785 CHEMBL1079421::Phenmedipham

SMILES: COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1

InChI Key: InChIKey=IDOWTHOLJBTAFI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311785   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50311785
PNG
(CHEMBL1079421 | Phenmedipham)
Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1
Show InChI InChI=1S/C16H16N2O4/c1-11-5-3-6-12(9-11)18-16(20)22-14-8-4-7-13(10-14)17-15(19)21-2/h3-10H,1-2H3,(H,17,19)(H,18,20)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 377n/an/an/an/an/an/a



Renovis Inc

Curated by ChEMBL


Assay Description
Inhibition of human FAAH


Bioorg Med Chem Lett 19: 6793-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.086
BindingDB Entry DOI: 10.7270/Q2BV7GRN
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579)


(Rattus norvegicus (rat))
BDBM50311785
PNG
(CHEMBL1079421 | Phenmedipham)
Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1
Show InChI InChI=1S/C16H16N2O4/c1-11-5-3-6-12(9-11)18-16(20)22-14-8-4-7-13(10-14)17-15(19)21-2/h3-10H,1-2H3,(H,17,19)(H,18,20)
PDB
MMDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 77n/an/an/an/an/an/a



Renovis Inc

Curated by ChEMBL


Assay Description
Inhibition of rat FAAH


Bioorg Med Chem Lett 19: 6793-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.086
BindingDB Entry DOI: 10.7270/Q2BV7GRN
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50311785
PNG
(CHEMBL1079421 | Phenmedipham)
Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1
Show InChI InChI=1S/C16H16N2O4/c1-11-5-3-6-12(9-11)18-16(20)22-14-8-4-7-13(10-14)17-15(19)21-2/h3-10H,1-2H3,(H,17,19)(H,18,20)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 152n/an/an/an/an/an/a



Renovis Inc

Curated by ChEMBL


Assay Description
Inhibition of human FAAH-mediated hydrolysis of [3H]AEA


Bioorg Med Chem Lett 19: 6793-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.086
BindingDB Entry DOI: 10.7270/Q2BV7GRN
More data for this
Ligand-Target Pair