Binding Database BindingDB logo


Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Found 9 hits with Target = 'HIV-1 Protease Mutant (L10I/L90M)'
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kJ/mole
-TΔS°
kJ/mole
ΔH°
kJ/mole
log KpHTemp
°C
HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
Lopinavir
JPEG
( ABT-378 | (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylph...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
PubMed
-62.2-55.6-6.6810.9525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
KNI-764
JPEG
((4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylph...)
B.MOAD
GoogleScholar
MMDB
PDB
CSLS
MMDB
PC cid
PC sid
PDB
PubMed
-60.6-33.0-27.510.6525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
ritonavir
JPEG
(1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
PubMed
-53.9-42.2-11.79.43525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
KNI-272
JPEG
((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(2R)-2-[...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
KEGG
MMDB
PC cid
PC sid
PDB
PubMed
-53.9-32.2-21.79.46525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
Amprenavir
JPEG
( 141W94 | Agenerase | (3S)-oxolan-3-yl N-[(2S,3R)...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
PubMed
-51.8-30.1-21.79.11525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
nelfinavir
JPEG
((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
PubMed
-50.5-70.6208.86525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
saquinavir
JPEG
((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
MMDB
PC cid
PC sid
PDB
PubMed
-50.1-65.2158.77525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
Indinavir
JPEG
((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)
B.MOAD
GoogleScholar
MMDB
PDB
CHEBI
CSLS
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
PubMed
-49.3-61.912.58.63525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

HIV-1 Protease Mutant (L10I/L90M)

(Human immunodeficiency virus type 1)
Acetyl Pepstatin
JPEG
(4-{2-[(3R)-4-[2-(2-acetamido-3-methylbutanamido)-3...)
B.MOAD
GoogleScholar
MMDB
PDB
CSLS
PC cid
PC sid
PubMed
-34.2-70.235.96.04525


Johns Hopkins University



Biochemistry. 42: 13659-66 (2003)

  • Reorder this table by ΔH°
  • Reorder this table by -TΔS°
  • Reorder this table by pH
  • Reorder this table by T
  • Change energy unit to:  kcal/mole
* indicates data uncertainty>20%