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Target
Sequence
Name
&
Ki
IC50
Kd
EC50
ΔG°
ΔH°
-TΔS°
pH (Enzymatic Assay)
pH (ITC)
Substrate or Competitor
Compound Mol. Wt.
Chemical Structure
Monomer List in csv
Het List in SDF
Compound
FDA Drugs
Chemical Structure
Batch Structures
Name
SMILES
Number of Data
/
Targets
Data Source
Author
Institution
PubMed
PubChem BioAssay
Other Databases
PDB
85%
100%
Seq ID
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
PubMed
Download
All Compounds & Data
Target Names &
Ki
IC50
Kd
EC50
ΔG°
ΔH°
-TΔS°
Virtual Screening
Forum
Enter Data
ITC
Enzyme Inhibition
Continue Deposition
Sent Comments
Compile Data Set for Download or QSAR
(2D
Computed 3D by
Vconf
-m prep
)
Data curated solely by
BindingDB
Found
4
hits of other Enz. Inhib. for enzyme = ATP Phosphoribosyltransferase with UniProtKB:
A5U4E7
Target
(Institution)
Ligand
Target
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
pH
Temp
°C
ATP Phosphoribosyltransferase
Mycobacterium tuberculosis
ChemBridge bis(benzylsulfanyl)pyrimidine, 15
(4,6-bis(benzylsulfanyl)pyrimidine-2,5-diamine)
B.MOAD
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
n/a
n/a
n/a
n/a
n/a
8.5
22
Yale University
J Med Chem.
51:
5984
-
92
(2008)
ATP Phosphoribosyltransferase
Mycobacterium tuberculosis
ChemBridge nitrobenzothiazole, 20
(2-[methyl(6-nitro-1,3-benzothiazol-2-yl)amino]acet...)
B.MOAD
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
n/a
n/a
n/a
n/a
n/a
8.5
22
Yale University
J Med Chem.
51:
5984
-
92
(2008)
ATP Phosphoribosyltransferase
Mycobacterium tuberculosis
ChemBridge pyrrolidine-2,3-dione, 1
((4E)-4-[(4-chlorophenyl)(hydroxy)methylidene]-1-(p...)
B.MOAD
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
n/a
n/a
n/a
n/a
n/a
8.5
22
Yale University
J Med Chem.
51:
5984
-
92
(2008)
ATP Phosphoribosyltransferase
Mycobacterium tuberculosis
ChemBridge dibenzenesulfonic acid, 16
(4-[(E)-2-{2,6-diamino-3-methyl-5-[(E)-2-(4-sulfoph...)
B.MOAD
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
n/a
n/a
n/a
n/a
n/a
8.5
22
Yale University
J Med Chem.
51:
5984
-
92
(2008)
Reorder this table by
ec50
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ic50
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kd
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pH
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T
Change energy unit to:
kcal/mole