Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for UniProtKB: P05653
TargetDNA gyrase subunit A/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21689(1-cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-...)
Affinity DataIC50:  5.60E+3nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  6.30E+3nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA gyrase subunit A/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)
Affinity DataIC50:  3.10E+4nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50:  1.49E+5nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Bacillus subtilis)
Microbiotix

LigandPNGBDBM21686(3-(4-hydroxybutyl)-6-(3-ethyl-4-methylanilino)urac...)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) is defined as the concentration of compound that inhibits the decatenation of kinetoplast DNA by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed