Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ec50 for monomerid = 20000
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  2.10nM EC50:  71nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  2.10nM EC50:  71nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human LXRbeta expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human LXRbeta ligand binding domain (219-462) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiva...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  2nM EC50:  90nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  2.10nM EC50:  93nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha [197-447](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  9.5nM EC50:  238nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human LXRalpha ligand binding domain (205-448) expressed in human HuH7 cells cotransfected with Gal4-DBD by luciferase transactiv...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human LXRalpha expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha [197-447](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  10nM EC50:  240nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM20000(2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  680nMAssay Description:Agonist activity at human recombinant PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed