Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ec50 for monomerid = 20877
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataEC50:  5.20nMAssay Description:Inhibition of human SGLT2 expressed in xenopus oocytes assessed as inhibition of [14C]AMG uptakeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataEC50:  6.60nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataEC50:  6.60nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataEC50:  50nMAssay Description:Inhibition of human SGLT2 expressed in Xenopus oocyte assessed as [14C]-alpha-methyl glucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataEC50:  211nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM20877(3-(1-benzofuran-5-yl)-1-(2-hydroxy-4-methyl-6-{[(2...)
Affinity DataEC50:  240nMAssay Description:Inhibition of human SGLT1 expressed in xenopus oocytes assessed as inhibition of [14C]AMG uptakeMore data for this Ligand-Target Pair
In DepthDetails PubMed