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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 1392   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Reverse Transcriptase


(Human immunodeficiency virus type 1)
BDBM1392
PNG
(1,2,3,9b-Tetrahydro-5H-pyrrolo[2,1-a]isoindol-5-on...)
Show SMILES O=C1N2CCCC2(c2ccccc12)c1ccccc1
Show InChI InChI=1/C17H15NO/c19-16-14-9-4-5-10-15(14)17(11-6-12-18(16)17)13-7-2-1-3-8-13/h1-5,7-10H,6,11-12H2
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Boehringer Mannheim GmbH



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 36: 2526-35 (1993)


Article DOI: 10.1021/jm00069a011
BindingDB Entry DOI: 10.7270/Q2BR8QCZ
More data for this
Ligand-Target Pair