Compile Data Set for Download or QSAR
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Found 5 of ic50 for monomerid = 14322
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase oxygenase [E25A,E26A,E316A](Bacillus subtilis)
University Of California Irvine

LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataIC50:  2.73E+4nMAssay Description:Reactions were carried out using the buffered solution reported for the three-component reaction. The bBiDomain reactions included 100 nm bBiDomain a...More data for this Ligand-Target Pair
TargetNitric oxide synthase oxygenase [E25A,E26A,I218V,E316A](Bacillus subtilis)
University Of California Irvine

LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataIC50:  6.39E+4nMAssay Description:Reactions were carried out using the buffered solution reported for the three-component reaction. The bBiDomain reactions included 100 nm bBiDomain a...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of BACE1 using 19F-labeled EVNLDAEF(CF3) as substrate after 20 mins by NMR spectrometeryMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataIC50:  2.00E+6nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair