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Found 4 of ic50 for monomerid = 15381
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM15381(8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pen...)
Affinity DataIC50:  660nMAssay Description:Displacement of GM-cy3B from Hsp90 in human SKBR3 cells after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM15381(8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pen...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM15381(8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pen...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of ATP-ase activity in human colon tumour cell line (HCT116)More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
Vernalis (R&D)

LigandPNGBDBM15381(8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pen...)
Affinity DataIC50:  3.00E+4nMpH: 7.4 T: 2°CAssay Description:The HSP90 ATPase activity was determined by following the procedure of malachite green assay. The assay is based on quantitation of the green complex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed