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Found 3 of ic50 for monomerid = 256870
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256870(US10654855, Example 66 | US11236095, Example 66 | ...)
Affinity DataIC50:  6.60nMpH: 7.5 T: 2°CAssay Description:This assay detects inhibitors of AKT1 (PKBα) kinase activity using Caliper LabChip LC3000. The Caliper off-chip incubation mobility shift assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256870(US10654855, Example 66 | US11236095, Example 66 | ...)
Affinity DataIC50:  6.60nMAssay Description:Following addition of compound or control to the assay plate, 6p1 peptide mix containing 3 μM substrate (5-FAM-GRPRTSSFAEG-CONH2; CRB) and 40 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM256870(US10654855, Example 66 | US11236095, Example 66 | ...)
Affinity DataIC50:  6.60nMAssay Description:For Echo dosing the solvent was 100% DMSO. A master plate was prepared with 40 ul of 10 mM stock from our Primary Liquid Store in quadrant 1 of a Lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent