Found 65 of ic50 for monomerid = 50018830 TargetProto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human EML4-fused ALK F1174L mutant expressed in mouse NIH-3T3 cells assessed as phospho-ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of wild type EML4/ALK F1174L mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen gamma chain/Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of CD74-ROS1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type EML4/ALK (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type human EML4-fused ALK expressed in mouse NIH-3T3 cells assessed as phosphorylated ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of wild type EML4/ALK C1156Y mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human EML4-fused ALK C1156Y mutant expressed in mouse NIH-3T3 cells assessed as phospho-ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of LTK (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of FER (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of wild type EML4/ALK S1206Y mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human EML4-fused ALK S1206Y mutant expressed in mouse NIH-3T3 cells assessed as phospho-ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:The inhibition of ALK tyrosine kinase activity can be demonstrated using known methods. For example, in one method, compounds can be tested for their...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of FES (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human EML4-fused ALK L1152R mutant expressed in mouse NIH-3T3 cells assessed as phospho-ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type EML4/ALK L1152R mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of PTK2B (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human EML4-fused ALK G1269A mutant expressed in mouse NIH-3T3 cells assessed as phospho-ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type EML4/ALK G1269A mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of PTK2 (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of TNK2 (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human EML4-fused ALK L1196M mutant expressed in mouse NIH-3T3 cells assessed as phospho-ALK level after 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Taibah University
Curated by ChEMBL
Taibah University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type EML4/ALK L1196M mutant (unknown origin) expressed in NIH/3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of NRTK1 (unknown origin) by TR-FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
