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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50036889   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50036889
PNG
(Benzo[d]isothiazole-3-carboxylic acid [4-(4-benzo[...)
Show SMILES CN(CCCCN1CCN(CC1)c1nsc2ccccc12)C(=O)c1nsc2ccccc12
Show InChI InChI=1S/C24H27N5OS2/c1-27(24(30)22-18-8-2-4-10-20(18)31-25-22)12-6-7-13-28-14-16-29(17-15-28)23-19-9-3-5-11-21(19)32-26-23/h2-5,8-11H,6-7,12-17H2,1H3
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Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
In vitro affinity towards 5-hydroxytryptamine 2A receptor using [3H]-spiroperidol as radioligand in cortex


J Med Chem 37: 2308-14 (1994)


Article DOI: 10.1021/jm00041a009
BindingDB Entry DOI: 10.7270/Q2QF8RXV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50036889
PNG
(Benzo[d]isothiazole-3-carboxylic acid [4-(4-benzo[...)
Show SMILES CN(CCCCN1CCN(CC1)c1nsc2ccccc12)C(=O)c1nsc2ccccc12
Show InChI InChI=1S/C24H27N5OS2/c1-27(24(30)22-18-8-2-4-10-20(18)31-25-22)12-6-7-13-28-14-16-29(17-15-28)23-19-9-3-5-11-21(19)32-26-23/h2-5,8-11H,6-7,12-17H2,1H3
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PC sid
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Article
PubMed
n/an/a 18.6n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
In vitro affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand in hippocampus


J Med Chem 37: 2308-14 (1994)


Article DOI: 10.1021/jm00041a009
BindingDB Entry DOI: 10.7270/Q2QF8RXV
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50036889
PNG
(Benzo[d]isothiazole-3-carboxylic acid [4-(4-benzo[...)
Show SMILES CN(CCCCN1CCN(CC1)c1nsc2ccccc12)C(=O)c1nsc2ccccc12
Show InChI InChI=1S/C24H27N5OS2/c1-27(24(30)22-18-8-2-4-10-20(18)31-25-22)12-6-7-13-28-14-16-29(17-15-28)23-19-9-3-5-11-21(19)32-26-23/h2-5,8-11H,6-7,12-17H2,1H3
PDB

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UniProtKB/SwissProt

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PC sid
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Article
PubMed
n/an/a 208n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
In vitro affinity towards D2 receptor using [3H]-spiroperidol as radioligand in striatum


J Med Chem 37: 2308-14 (1994)


Article DOI: 10.1021/jm00041a009
BindingDB Entry DOI: 10.7270/Q2QF8RXV
More data for this
Ligand-Target Pair