TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of AchE in Rattus norvegicus (rat) cortex homogenates by Ellman's methodMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human AKR1C3 expressed in Escherichia coli BL21 (D3) using oracin as substrate measured after 30 mins in presence of NADPH ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant His-tagged AKR1C3 expressed in Escherichia coli BL21(DE3) incubated for 30 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as reduction in DHT-induced transcriptional activation after 24 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as reduction in DHT-induced cell growth treated for every 2 days for 4 days by hemocytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK-293 cells incubated for 10 minsMore data for this Ligand-Target Pair