Found 19 of ic50 for monomerid = 50103521 TargetBile salt export pump(Homo sapiens (Human))
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human BSEP expressed in HEK293 cell membrane vesicles assessed as reduction in 3H-TCA uptake incubated for 5 mins by radiodetection met...More data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Affinity DataIC50: 262nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Comsats University Islamabad
Curated by ChEMBL
Comsats University Islamabad
Curated by ChEMBL
Affinity DataIC50: 298nMAssay Description:Inhibition of recombinant human MAO-BMore data for this Ligand-Target Pair
3D Structure (crystal)TargetBile salt export pump(Homo sapiens (Human))
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptorMore data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Norman Drug Discovery Training And Consulting
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
TargetCDGSH iron-sulfur domain-containing protein 1(Rattus norvegicus)
Northeastern Ohio Universities
Curated by ChEMBL
Northeastern Ohio Universities
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]rosiglitazone from rat liver mitochondrial mitoNEET by scintillation countingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Terns Pharmaceuticals
Curated by ChEMBL
Terns Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Activation of mouse liver PPARalphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of FITC-NCoR1 peptide from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia coli BL21(DE3) after...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of FITC-NCoR1 peptide from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia coli BL21(DE3) after...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 1.79E+3nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
TargetCDGSH iron-sulfur domain-containing protein 2(Homo sapiens)
West Virginia University
Curated by ChEMBL
West Virginia University
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged NAF1 expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCDGSH iron-sulfur domain-containing protein 1(Homo sapiens (Human))
West Virginia University
Curated by ChEMBL
West Virginia University
Curated by ChEMBL
Affinity DataIC50: 8.65E+3nMAssay Description:Displacement of [3H]rosiglitazone from recombinant human C-terminal His-tagged MitoNEET cytosolic domain (32 to 108 residues) expressed in Escherichi...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Transrepression activity at human PPARgamma expressed in HEK293 cells assessed as inhibition of TNFalpha induced NF-kappaB promoter activity pretreat...More data for this Ligand-Target Pair
Affinity DataIC50: 4.95E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
