TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
The Rockefeller University
Curated by ChEMBL
The Rockefeller University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of GSK3-betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Cdk5Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mammalian CDK5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of cyclin-dependent kinase 5/p25More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Cdk1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant aurora C kinaseMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of against CDK2/cyclinE1 (unknown origin) using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate and ATP incubated for 15 mins by fluorescence ba...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant aurora B kinaseMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Sciences And Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of against CDK9/cyclinT1 (unknown origin) using Ulight-CFFKNIVTPRTPPPSQGK-amide substrate and ATP incubated for 90 mins by fluorescence ba...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant aurora A kinaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 20 uM A23187/AA ionopho...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 2.5 uM A23187 ionophoreMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University
Curated by ChEMBL
Friedrich-Schiller-University
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to controlMore data for this Ligand-Target Pair
TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Plasmodium falciparum cyclin-dependent kinaseMore data for this Ligand-Target Pair
TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Walter Reed Army Institute Of Research
Curated by ChEMBL
Walter Reed Army Institute Of Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinase, PfmrkMore data for this Ligand-Target Pair