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Found 4 of ic50 for monomerid = 50171916
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50171916(CHEMBL3805299 | US10106508, Compound I-11)
Affinity DataIC50:  75nMAssay Description:Inhibition of wild type EGFR (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 hr by kinase-glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50171916(CHEMBL3805299 | US10106508, Compound I-11)
Affinity DataIC50: <100nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM50171916(CHEMBL3805299 | US10106508, Compound I-11)
Affinity DataIC50: <1.00E+3nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing University Of Technology

Curated by ChEMBL
LigandPNGBDBM50171916(CHEMBL3805299 | US10106508, Compound I-11)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) autophosphorylation preincubated for 30 mins followed by ATP addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed