TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of gamma-secretase assessed as reduction of cell Abeta40 levelMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP3A4 after 30 minsMore data for this Ligand-Target Pair