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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50315924   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50315924
PNG
((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Show SMILES CCN(C(=O)c1csc2ccccc12)c1ccnc(N[C@@H](C)c2ccccc2)n1
Show InChI InChI=1/C23H22N4OS/c1-3-27(22(28)19-15-29-20-12-8-7-11-18(19)20)21-13-14-24-23(26-21)25-16(2)17-9-5-4-6-10-17/h4-16H,3H2,1-2H3,(H,24,25,26)/t16-/s2
PDB
MMDB

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UniProtKB/SwissProt
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PC cid
PC sid
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Patents

Article
PubMed
n/an/a 188n/an/an/an/an/an/a



Scios Inc

Curated by ChEMBL


Assay Description
Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting


Bioorg Med Chem Lett 20: 2560-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.090
BindingDB Entry DOI: 10.7270/Q2BV7GS3
More data for this
Ligand-Target Pair