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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50321730   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase receptor Ret


(Homo sapiens (Human))
BDBM50321730
PNG
(2-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-4-(3-t...)
Show SMILES Clc1ccc(cc1)C(=O)CSc1nc2CCCCc2c(-c2ccsc2)c1C#N
Show InChI InChI=1S/C22H17ClN2OS2/c23-16-7-5-14(6-8-16)20(26)13-28-22-18(11-24)21(15-9-10-27-12-15)17-3-1-2-4-19(17)25-22/h5-10,12H,1-4,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



Technische Universit£t Braunschweig

Curated by ChEMBL


Assay Description
Inhibition of human recombinant histidine-tagged RET (700-1020) expressed in Sf9 cells by ELISA


Eur J Med Chem 45: 2919-27 (2010)


Article DOI: 10.1016/j.ejmech.2010.03.017
BindingDB Entry DOI: 10.7270/Q25X294R
More data for this
Ligand-Target Pair