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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50346048   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50346048
PNG
(8-methyl-2-(1-methylpiperidin-4-yl)-5-(2-(pyridin-...)
Show SMILES CN1CCC(CC1)N1CCc2c(C1)c1cc(C)ccc1n2CCc1ccncc1
Show InChI InChI=1S/C25H32N4/c1-19-3-4-24-22(17-19)23-18-28(21-8-13-27(2)14-9-21)15-10-25(23)29(24)16-7-20-5-11-26-12-6-20/h3-6,11-12,17,21H,7-10,13-16,18H2,1-2H3
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PC sid
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Article
PubMed
n/an/a 7.57E+3n/an/an/an/an/an/a



Chemical Diversity Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H1 receptor in SK-N-SH cells assessed as inhibition of histamine-induced calcium level increase during phase-1...


Bioorg Med Chem Lett 19: 3183-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.128
BindingDB Entry DOI: 10.7270/Q2FJ2H4X
More data for this
Ligand-Target Pair