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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50358772   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50358772
PNG
(CHEMBL1922599)
Show SMILES Clc1cc2c(cc1Nc1cccc(NC(=O)c3cccc(c3)C#N)c1)c(=O)[nH][nH]c2=O
Show InChI InChI=1S/C22H14ClN5O3/c23-18-9-16-17(22(31)28-27-21(16)30)10-19(18)25-14-5-2-6-15(8-14)26-20(29)13-4-1-3-12(7-13)11-24/h1-10,25H,(H,26,29)(H,27,30)(H,28,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 296n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant his6-tagged B-Raf expressed in Sf9 cells assessed as inhibition of MEK1 phosphorylation after 60 mins


Bioorg Med Chem Lett 21: 6941-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.012
BindingDB Entry DOI: 10.7270/Q21R6QXK
More data for this
Ligand-Target Pair