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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50382392   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50382392
PNG
(CHEMBL2022158)
Show SMILES Brc1cccc(NC(=O)NC2=NC(=O)CCN2)c1
Show InChI InChI=1S/C11H11BrN4O2/c12-7-2-1-3-8(6-7)14-11(18)16-10-13-5-4-9(17)15-10/h1-3,6H,4-5H2,(H3,13,14,15,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO-K1 cells assessed as inhibition of glutamate-induced intracellular calcium mobilization


ACS Med Chem Lett 2: 882-884 (2011)


Article DOI: 10.1021/ml200162f
BindingDB Entry DOI: 10.7270/Q2XW4KT8
More data for this
Ligand-Target Pair