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Found 9 of ic50 for monomerid = 50402023
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PLK1 (1 to 603 residues) expressed in baculovirus expression system using casein as substrate i...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human PLK1 (1 to 603 residues) expressed in baculovirus expression system using bovine milk casein as...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  0.870nMAssay Description:Competitive inhibition of human PLK1 in presence of ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of NH2-terminal GST-tagged recombinant human Plk1 (1 to 603 residues) expressed in baculovirus expression system using casein as substrate...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human PLK1 using casein as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails MMDB
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  1.07E+3nMAssay Description:Displacement of biotin-PEG2- SGRGKacGGKacGLGKacGGAKacRHPvK-COOH from BRD4 (unknown origin) after 1.5 hrs by acetyl-histone binding based Alphascreen ...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  1.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50:  9.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails