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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50416374   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))
BDBM50416374
PNG
(CHEMBL1210501)
Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1F
Show InChI InChI=1S/C14H15F2N3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)
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UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 158n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human P2X7 receptor ethidium bromide release assay


Bioorg Med Chem Lett 20: 4653-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.107
BindingDB Entry DOI: 10.7270/Q2DZ09HF
More data for this
Ligand-Target Pair