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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50460872   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 7


(Homo sapiens (Human))
BDBM50460872
PNG
(CHEMBL4227530)
Show SMILES COc1ccc(Cl)cc1C[C@@H]1CN\C(CN(CC(=O)Nc2cccc(c2)-c2ccsc2)C1=O)=N/N(C)C
Show InChI InChI=1S/C27H30ClN5O3S/c1-32(2)31-25-15-33(16-26(34)30-23-6-4-5-18(13-23)19-9-10-37-17-19)27(35)21(14-29-25)11-20-12-22(28)7-8-24(20)36-3/h4-10,12-13,17,21H,11,14-16H2,1-3H3,(H,29,31)(H,30,34)/t21-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Asubio Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by s...


Bioorg Med Chem Lett 28: 1371-1375 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.011
BindingDB Entry DOI: 10.7270/Q2222XD7
More data for this
Ligand-Target Pair