Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of ic50 for monomerid = 60994
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Sanofi Research Division

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  5.80nMAssay Description:Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  5.80nMAssay Description:Compound was evaluated for the inhibition of [3H]WIN-55212-2 binding in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  9.5nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  218nMAssay Description:The compound was tested in vitro for binding activity against THC cannabinoid receptor site, using 3H-CP-55940 as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
Eth Z�Rich

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of human ABHD12 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 55(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  1.42E+4nMAssay Description:Antagonist activity at human GPR55 transfected in CHO cells assessed as inhibition of LPI-induced beta-arrestin recruitment incubated 60 mins prior t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Eth Z�Rich

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  4.36E+4nMAssay Description:Inhibition of FAAH (unknown origin) in human U-937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Eth Z�Rich

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50:  4.82E+4nMAssay Description:Inhibition of human ABHD6 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Eth Z�Rich

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAGL (unknown origin) in human U-937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed