Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ABL1 (c-Abl) (Homo sapiens (Human)) | BDBM185674![]() (4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)ca...) | PDB GoogleScholar AffyNet ![]() | Purchase PDB UniChem Similars AffyNet ![]() | PDB Article PubMed | n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a |
Stony Brook University | Assay Description Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against a panel... | ACS Chem Biol 11: 1296-304 (2016) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Proto-oncogene tyrosine-protein kinase Src (c-Src) (Gallus gallus (Chicken)) | BDBM185674![]() (4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)ca...) | PDB GoogleScholar AffyNet ![]() | Purchase PDB UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a |
Stony Brook University | Assay Description Inhibitor selectivity profiles were obtained through Luceome Biotechnologies (Tuscon, AZ). Each inhibitor was screened at 0.5 μM against phospho... | ACS Chem Biol 11: 1296-304 (2016) | |||||||||||
More data for this Ligand-Target Pair |