Found 780 of kd for monomerid = 5445 TargetEpidermal growth factor receptor [G719C](Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 0.920nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 0.920nMAssay Description:Binding constant for EGFR(G719C) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 0.920nMAssay Description:Binding constant for EGFR(G719C) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding constant for EGFR(L861Q) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Binding constant for EGFR(L861Q) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Binding constant for EGFR(G719S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Binding constant for EGFR(G719S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.20nMAssay Description:Binding constant for EGFR(L747-E749del, A750P) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.20nMAssay Description:Binding constant for EGFR(L747-E749del, A750P) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Inhibition of recombinant human partial length EGFR L858R mutant (669 to 1011 residues) expressed in bacterial expression system by competitive bindi...More data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Binding constant for EGFR(L858R) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.80nMAssay Description:Binding constant for EGFR(L858R) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding constant for EGFR(L747-T751del,Sins) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.5nMAssay Description:Binding constant for EGFR(L747-T751del,Sins) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding constant for EGFR(L747-S752del, P753S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding constant for EGFR(L747-S752del, P753S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding constant for EGFR(S752-I759del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding constant for EGFR(S752-I759del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 5.5nMAssay Description:Average Binding Constant for EGFR; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 7nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 7nMAssay Description:Binding constant for ERBB2 kinase domainMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 7nMAssay Description:Binding constant for ERBB2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 8.60nMAssay Description:Binding constant for EGFR(E746-A750del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 8.60nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 8.60nMAssay Description:Binding constant for EGFR(E746-A750del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to wild-type human partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 11nMAssay Description:Average Binding Constant for ERBB2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 54nMAssay Description:Binding constant for ERBB4 kinase domainMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 54nMAssay Description:Binding constant for ERBB4 kinase domainMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 54nMAssay Description:Inhibition of recombinant human wild type partial length HER4 (690 to 994 residues) expressed in bacterial expression system by competitive binding a...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 670nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 860nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 940nMAssay Description:Binding constant for PIK4CB kinase domainMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for MEK5 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Average Binding Constant for STK10; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 2.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetSTE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 3.30E+3nMAssay Description:Binding constant for SLK kinase domainMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 3.60E+3nMAssay Description:Binding constant for RIPK2 kinase domainMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 3.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 3.60E+3nMAssay Description:Binding constant for RIPK2 kinase domainMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 4.40E+3nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair
