Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ki for monomerid = 50417257
TargetOrexin receptor type 2(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.0776nMAssay Description:Antagonist activity at recombinant rat OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.117nMAssay Description:Antagonist activity at recombinant rat OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to orexin receptor 1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.316nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.316nMAssay Description:Antagonist activity against human orexin 1 receptor expressed in CHO cells assessed as effect in calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.398nMAssay Description:Antagonist activity against human orexin 2 receptor expressed in CHO cells assessed as effect in calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.398nMAssay Description:Antagonist activity at recombinant human OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  0.759nMAssay Description:Displacement of [3H]almorexant from recombinant human OX1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  1.29nMAssay Description:Displacement of [3H]almorexant from recombinant human OX2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417257(SB-649868)
Affinity DataKi:  8.5nMAssay Description:Displacement of [125I]-Orexin A from human OX2R expressed in CHO cells after 30 mins by topcount analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed