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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial' and Ligand = 'BDBM137693'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial


(Homo sapiens (Human))
BDBM137693
PNG
(US8871934, 286)
Show SMILES Cn1cc(cn1)-c1cc(Cl)cc2c1-c1ccccc1C2(O)C(F)(F)F
Show InChI InChI=1S/C18H12ClF3N2O/c1-24-9-10(8-23-24)13-6-11(19)7-15-16(13)12-4-2-3-5-14(12)17(15,25)18(20,21)22/h2-9,25H,1H3
PDB

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PC cid
PC sid
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Similars

US Patent
n/an/a 17n/an/an/an/a8.030



Japan Tobacco Inc

US Patent


Assay Description
The inhibitory action of PDHK activity was indirectly evaluated by performing a kinase reaction in the presence of a test compound and measuring the ...


US Patent US8871934 (2014)


BindingDB Entry DOI: 10.7270/Q2JQ0ZQT
More data for this
Ligand-Target Pair