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Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50224203'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224203(2-(2-chlorophenylamino)-5-cyclohexylthiazol-4(5H)-...)
Affinity DataKi:  11nMAssay Description:Inhibition of human 11betaHSD1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50224203(2-(2-chlorophenylamino)-5-cyclohexylthiazol-4(5H)-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed