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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50429307'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM50429307
PNG
(CHEMBL2334156)
Show SMILES CC1(C)C(C(=O)N2CCC[C@@H](C2)c2nc(no2)-c2ccccc2)C1(C)C
Show InChI InChI=1S/C21H27N3O2/c1-20(2)16(21(20,3)4)19(25)24-12-8-11-15(13-24)18-22-17(23-26-18)14-9-6-5-7-10-14/h5-7,9-10,15-16H,8,11-13H2,1-4H3/t15-/m0/s1
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MMDB

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Similars

Article
PubMed
n/an/a 793n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human 11-beta HSD1 transfected in HEK293 cell microsomes assessed as decrease in [3H]cortisol generation using [3H]cortisone as substra...


Eur J Med Chem 62: 1-10 (2013)


Article DOI: 10.1016/j.ejmech.2012.12.059
BindingDB Entry DOI: 10.7270/Q2GH9K9M
More data for this
Ligand-Target Pair