Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50399615'
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataKi:  13.1nMAssay Description:Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Universit£ de Caen Basse-Normandie

Curated by ChEMBL
LigandPNGBDBM50399615(CHEMBL2181171)
Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1
Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3
Affinity DataEC50:  10nMAssay Description:Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activationMore data for this Ligand-Target Pair